Cargando…

Artemether attenuates LPS-induced inflammatory bone loss by inhibiting osteoclastogenesis and bone resorption via suppression of MAPK signaling pathway

Osteolysis is an osteolytic lesion featured by enhanced osteoclast formation and potent bone erosion. Lacking of effective regimen for treatment of the pathological process highlights the importance of identifying agents that can suppress the differentiation and function of osteoclast. Artemether is...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Haobo, Hu, Bin, Zhou, Xiaopeng, Zhou, Chenhe, Meng, Jiahong, Yang, Yute, Zhao, Xiang, Shi, Zhongli, Yan, Shigui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924411/
https://www.ncbi.nlm.nih.gov/pubmed/29703893
http://dx.doi.org/10.1038/s41419-018-0540-y