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MR-Guided Delivery of AAV2-BDNF into the Entorhinal Cortex of Non-Human Primates
Brain-derived neurotrophic factor (BDNF) gene delivery to the entorhinal cortex is a candidate for treatment of Alzheimer’s disease (AD) to reduce neurodegeneration that is associated with memory loss. Accurate targeting of the entorhinal cortex in AD is complex due to the deep and atrophic state of...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924461/ https://www.ncbi.nlm.nih.gov/pubmed/29535375 http://dx.doi.org/10.1038/s41434-018-0010-2 |