Cargando…

Kinetics and Thermodynamics of DNA Processing by Wild Type DNA-Glycosylase Endo III and Its Catalytically Inactive Mutant Forms

Endonuclease III (Endo III or Nth) is one of the key enzymes responsible for initiating the base excision repair of oxidized or reduced pyrimidine bases in DNA. In this study, a thermodynamic analysis of structural rearrangements of the specific and nonspecific DNA-duplexes during their interaction...

Descripción completa

Detalles Bibliográficos
Autores principales: Kladova, Olga A., Krasnoperov, Lev N., Kuznetsov, Nikita A., Fedorova, Olga S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924532/
https://www.ncbi.nlm.nih.gov/pubmed/29601551
http://dx.doi.org/10.3390/genes9040190