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Identification of a WNT5A-Responsive Degradation Domain in the Kinesin Superfamily Protein KIF26B

Noncanonical WNT pathways function independently of the β-catenin transcriptional co-activator to regulate diverse morphogenetic and pathogenic processes. Recent studies showed that noncanonical WNTs, such as WNT5A, can signal the degradation of several downstream effectors, thereby modulating these...

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Detalles Bibliográficos
Autores principales: Karuna, Edith P., Choi, Shannon S., Scales, Michael K., Hum, Jennie, Cohen, Michael, Fierro, Fernando A., Ho, Hsin-Yi Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924538/
https://www.ncbi.nlm.nih.gov/pubmed/29621187
http://dx.doi.org/10.3390/genes9040196