Gene Therapy for Chronic HBV—Can We Eliminate cccDNA?

Chronic infection with the hepatitis B virus (HBV) is a global health concern and accounts for approximately 1 million deaths annually. Amongst other limitations of current anti-HBV treatment, failure to eliminate the viral covalently closed circular DNA (cccDNA) and emergence of resistance remain t...

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Detalles Bibliográficos
Autores principales: Bloom, Kristie, Maepa, Mohube Betty, Ely, Abdullah, Arbuthnot, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924549/
https://www.ncbi.nlm.nih.gov/pubmed/29649127
http://dx.doi.org/10.3390/genes9040207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924549/
https://www.ncbi.nlm.nih.gov/pubmed/29649127
http://dx.doi.org/10.3390/genes9040207

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