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Gene Therapy for Chronic HBV—Can We Eliminate cccDNA?

Chronic infection with the hepatitis B virus (HBV) is a global health concern and accounts for approximately 1 million deaths annually. Amongst other limitations of current anti-HBV treatment, failure to eliminate the viral covalently closed circular DNA (cccDNA) and emergence of resistance remain t...

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Detalles Bibliográficos
Autores principales:	Bloom, Kristie, Maepa, Mohube Betty, Ely, Abdullah, Arbuthnot, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924549/ https://www.ncbi.nlm.nih.gov/pubmed/29649127 http://dx.doi.org/10.3390/genes9040207

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