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Multicenter validation of cancer gene panel-based next-generation sequencing for translational research and molecular diagnostics

The simultaneous detection of multiple somatic mutations in the context of molecular diagnostics of cancer is frequently performed by means of amplicon-based targeted next-generation sequencing (NGS). However, only few studies are available comparing multicenter testing of different NGS platforms an...

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Detalles Bibliográficos
Autores principales: Hirsch, B., Endris, V., Lassmann, S., Weichert, W., Pfarr, N., Schirmacher, P., Kovaleva, V., Werner, M., Bonzheim, I., Fend, F., Sperveslage, J., Kaulich, K., Zacher, A., Reifenberger, G., Köhrer, K., Stepanow, S., Lerke, S., Mayr, T., Aust, D. E., Baretton, G., Weidner, S., Jung, A., Kirchner, T., Hansmann, M. L., Burbat, L., von der Wall, E., Dietel, M., Hummel, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924673/
https://www.ncbi.nlm.nih.gov/pubmed/29374318
http://dx.doi.org/10.1007/s00428-017-2288-7