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Palmitic acid induces neurotoxicity and gliatoxicity in SH-SY5Y human neuroblastoma and T98G human glioblastoma cells

BACKGROUND: Obesity-related central nervous system (CNS) pathologies like neuroinflammation and reactive gliosis are associated with high-fat diet (HFD) related elevation of saturated fatty acids like palmitic acid (PA) in neurons and astrocytes of the brain. METHODS: Human neuroblastoma cells SH-SY...

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Detalles Bibliográficos
Autores principales: Ng, Yee-Wen, Say, Yee-How
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924683/
https://www.ncbi.nlm.nih.gov/pubmed/29713567
http://dx.doi.org/10.7717/peerj.4696