O-GlcNAc elevation through activation of the hexosamine biosynthetic pathway enhances cancer cell chemoresistance

Chemoresistance has become a major obstacle to the success of cancer therapy, but the mechanisms underlying chemoresistance are not yet fully understood. O-GlcNAcylation is a post-translational modification that is regulated by the hexosamine biosynthetic pathway (HBP) and has an important role in a...

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Detalles Bibliográficos
Autores principales: Liu, Yubo, Cao, Yu, Pan, Xiaoqing, Shi, Meiyun, Wu, Qiong, Huang, Tianmiao, Jiang, Hui, Li, Wenli, Zhang, Jianing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924752/
https://www.ncbi.nlm.nih.gov/pubmed/29706631
http://dx.doi.org/10.1038/s41419-018-0522-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924752/
https://www.ncbi.nlm.nih.gov/pubmed/29706631
http://dx.doi.org/10.1038/s41419-018-0522-0

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