Long non-coding RNA Lnc-Tim3 exacerbates CD8 T cell exhaustion via binding to Tim-3 and inducing nuclear translocation of Bat3 in HCC

Although one of the first comprehensive examinations of long non-coding RNA (lncRNA) expression was performed in human CD8 T lymphocytes, little is known about their roles in CD8 T cells functions during the progression of hepatocellular carcinoma (HCC). Here, we show that Lnc-Tim3 is upregulated an...

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Detalles Bibliográficos
Autores principales: Ji, Jie, Yin, Yin, Ju, Huanyu, Xu, Xiaoliang, Liu, Wei, Fu, Qiang, Hu, Jiaojiao, Zhang, Xudong, Sun, Beicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924754/
https://www.ncbi.nlm.nih.gov/pubmed/29706626
http://dx.doi.org/10.1038/s41419-018-0528-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924754/
https://www.ncbi.nlm.nih.gov/pubmed/29706626
http://dx.doi.org/10.1038/s41419-018-0528-7

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