Cargando…

Understanding Viral dsRNA-Mediated Innate Immune Responses at the Cellular Level Using a Rainbow Trout Model

Viruses across genome types produce long dsRNA molecules during replication [viral (v-) dsRNA]. dsRNA is a potent signaling molecule and inducer of type I interferon (IFN), leading to the production of interferon-stimulated genes (ISGs), and a protective antiviral state within the cell. Research on...

Descripción completa

Detalles Bibliográficos
Autores principales: Poynter, Sarah J., DeWitte-Orr, Stephanie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924774/
https://www.ncbi.nlm.nih.gov/pubmed/29740439
http://dx.doi.org/10.3389/fimmu.2018.00829