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Hydroxybenzoic Acid Derivatives as Dual-Target Ligands: Mitochondriotropic Antioxidants and Cholinesterase Inhibitors

Alzheimer's disease (AD) is a multifactorial age-related disease associated with oxidative stress (OS) and impaired cholinergic transmission. Accordingly, targeting mitochondrial OS and restoring cholinergic transmission can be an effective therapeutic strategy toward AD. Herein, we report for...

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Detalles Bibliográficos
Autores principales: Oliveira, Catarina, Cagide, Fernando, Teixeira, José, Amorim, Ricardo, Sequeira, Lisa, Mesiti, Francesco, Silva, Tiago, Garrido, Jorge, Remião, Fernando, Vilar, Santiago, Uriarte, Eugenio, Oliveira, Paulo J., Borges, Fernanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924788/
https://www.ncbi.nlm.nih.gov/pubmed/29740575
http://dx.doi.org/10.3389/fchem.2018.00126