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Hydroxybenzoic Acid Derivatives as Dual-Target Ligands: Mitochondriotropic Antioxidants and Cholinesterase Inhibitors
Alzheimer's disease (AD) is a multifactorial age-related disease associated with oxidative stress (OS) and impaired cholinergic transmission. Accordingly, targeting mitochondrial OS and restoring cholinergic transmission can be an effective therapeutic strategy toward AD. Herein, we report for...
Autores principales: | Oliveira, Catarina, Cagide, Fernando, Teixeira, José, Amorim, Ricardo, Sequeira, Lisa, Mesiti, Francesco, Silva, Tiago, Garrido, Jorge, Remião, Fernando, Vilar, Santiago, Uriarte, Eugenio, Oliveira, Paulo J., Borges, Fernanda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924788/ https://www.ncbi.nlm.nih.gov/pubmed/29740575 http://dx.doi.org/10.3389/fchem.2018.00126 |
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