Induction of Type I Interferons by Therapeutic Nanoparticle-Based Vaccination Is Indispensable to Reinforce Cytotoxic CD8(+) T Cell Responses During Chronic Retroviral Infection

T cell dysfunction and immunosuppression are characteristic for chronic viral infections and contribute to viral persistence. Overcoming these burdens is the goal of new therapeutic strategies to cure chronic infectious diseases. We recently described that therapeutic vaccination of chronic retrovir...

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Detalles Bibliográficos
Autores principales: Knuschke, Torben, Rotan, Olga, Bayer, Wibke, Kollenda, Sebastian, Dickow, Julia, Sutter, Kathrin, Hansen, Wiebke, Dittmer, Ulf, Lang, Karl S., Epple, Matthias, Buer, Jan, Westendorf, Astrid M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924795/
https://www.ncbi.nlm.nih.gov/pubmed/29740425
http://dx.doi.org/10.3389/fimmu.2018.00614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924795/
https://www.ncbi.nlm.nih.gov/pubmed/29740425
http://dx.doi.org/10.3389/fimmu.2018.00614

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