Cargando…

Translation initiation in bacterial polysomes through ribosome loading on a standby site on a highly translated mRNA

During translation, consecutive ribosomes load on an mRNA and form a polysome. The first ribosome binds to a single-stranded mRNA region and moves toward the start codon, unwinding potential mRNA structures on the way. In contrast, the following ribosomes can dock at the start codon only when the fi...

Descripción completa

Detalles Bibliográficos
Autores principales: Andreeva, Irena, Belardinelli, Riccardo, Rodnina, Marina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924895/
https://www.ncbi.nlm.nih.gov/pubmed/29632209
http://dx.doi.org/10.1073/pnas.1718029115