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Translation initiation in bacterial polysomes through ribosome loading on a standby site on a highly translated mRNA
During translation, consecutive ribosomes load on an mRNA and form a polysome. The first ribosome binds to a single-stranded mRNA region and moves toward the start codon, unwinding potential mRNA structures on the way. In contrast, the following ribosomes can dock at the start codon only when the fi...
Autores principales: | Andreeva, Irena, Belardinelli, Riccardo, Rodnina, Marina V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924895/ https://www.ncbi.nlm.nih.gov/pubmed/29632209 http://dx.doi.org/10.1073/pnas.1718029115 |
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