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Intermittent High Glucose Exacerbates A-FABP Activation and Inflammatory Response through TLR4-JNK Signaling in THP-1 Cells

BACKGROUND: Glucose fluctuation confers additional risks on diabetes-related vascular diseases, but the underlying mechanisms are unknown. Macrophage activation mediated by TLR4-JNK signaling plays an important role during the progress of diabetes. In the present study, we hypothesize that glucose f...

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Detalles Bibliográficos
Autores principales: Li, Hui, Luo, Han-Ying, Liu, Qing, Xiao, Yang, Tang, Lin, Zhong, Feng, Huang, Gan, Xu, Jun-Mei, Xu, Ai-Min, Zhou, Zhi-Guang, Dai, Ru-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925160/
https://www.ncbi.nlm.nih.gov/pubmed/29850615
http://dx.doi.org/10.1155/2018/1319272