p66Shc Mediates Mitochondrial Dysfunction Dependent on PKC Activation in Airway Epithelial Cells Induced by Cigarette Smoke

Airway epithelial mitochondrial injury plays a critical role in the pathogenesis of chronic obstructive pulmonary disease (COPD). The p66Shc adaptor protein is a newly recognized mediator of mitochondrial dysfunction. However, little is known about the effect of p66Shc on airway epithelial damage in...

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Detalles Bibliográficos
Autores principales: Zhang, Ming, Tang, Jingjing, Shan, Hu, Zhang, Qiuhong, Yang, Xia, Zhang, Jie, Li, Yali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925171/
https://www.ncbi.nlm.nih.gov/pubmed/29849902
http://dx.doi.org/10.1155/2018/5837123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925171/
https://www.ncbi.nlm.nih.gov/pubmed/29849902
http://dx.doi.org/10.1155/2018/5837123

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