Antihyperuricemic effect of mangiferin aglycon derivative J99745 by inhibiting xanthine oxidase activity and urate transporter 1 expression in mice

A mangiferin aglycon derivative J99745 has been identified as a potent xanthine oxidase (XOD) inhibitor by previous in vitro study. This study aimed to evaluate the hypouricemic effects of J99745 in experimental hyperuricemia mice, and explore the underlying mechanisms. Mice were orally administered...

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Detalles Bibliográficos
Autores principales: Qin, Zhizhen, Wang, Shoubao, Lin, Yihuang, Zhao, Ying, Yang, Shengqian, Song, Junke, Xie, Tao, Tian, Jinlong, Wu, Song, Du, Guanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925220/
https://www.ncbi.nlm.nih.gov/pubmed/29719791
http://dx.doi.org/10.1016/j.apsb.2017.05.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925220/
https://www.ncbi.nlm.nih.gov/pubmed/29719791
http://dx.doi.org/10.1016/j.apsb.2017.05.004

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