Establishment of pseudovirus infection mouse models for in vivo pharmacodynamics evaluation of filovirus entry inhibitors

Filoviruses cause severe and fatal viral hemorrhagic fever in humans. Filovirus research has been extensive since the 2014 Ebola outbreak. Due to their high pathogenicity and mortality, live filoviruses require Biosafety Level-4 (BSL-4) facilities, which have restricted the development of anti-filov...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Qing, Tang, Ke, Zhang, Xiaoyu, Chen, Panpan, Guo, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925413/
https://www.ncbi.nlm.nih.gov/pubmed/29719780
http://dx.doi.org/10.1016/j.apsb.2017.08.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925413/
https://www.ncbi.nlm.nih.gov/pubmed/29719780
http://dx.doi.org/10.1016/j.apsb.2017.08.003

Ejemplares similares