Separation and simultaneous quantitation of PGF2α and its epimer 8-iso-PGF2α using modifier-assisted differential mobility spectrometry tandem mass spectrometry

Because many therapeutic agents are contaminated by epimeric impurities or form epimers as a result of metabolism, analytical tools capable of determining epimers are increasingly in demand. This article is a proof-of-principle report of a novel DMS–MS/MS method to separate and simultaneously quanti...

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Detalles Bibliográficos
Autores principales: Liang, Chunsu, Sun, Hui, Meng, Xiangjun, Yin, Lei, Fawcett, J. Paul, Yu, Huaidong, Liu, Ting, Gu, Jingkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925447/
https://www.ncbi.nlm.nih.gov/pubmed/29719783
http://dx.doi.org/10.1016/j.apsb.2018.01.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925447/
https://www.ncbi.nlm.nih.gov/pubmed/29719783
http://dx.doi.org/10.1016/j.apsb.2018.01.011

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