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Prostaglandin D2 Receptor DP1 Antibodies Predict Vaccine-induced and Spontaneous Narcolepsy Type 1: Large-scale Study of Antibody Profiling

BACKGROUND: Neuropathological findings support an autoimmune etiology as an underlying factor for loss of orexin-producing neurons in spontaneous narcolepsy type 1 (narcolepsy with cataplexy; sNT1) as well as in Pandemrix influenza vaccine-induced narcolepsy type 1 (Pdmx-NT1). The precise molecular...

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Detalles Bibliográficos
Autores principales: Sadam, Helle, Pihlak, Arno, Kivil, Anri, Pihelgas, Susan, Jaago, Mariliis, Adler, Priit, Vilo, Jaak, Vapalahti, Olli, Neuman, Toomas, Lindholm, Dan, Partinen, Markku, Vaheri, Antti, Palm, Kaia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925455/
https://www.ncbi.nlm.nih.gov/pubmed/29449194
http://dx.doi.org/10.1016/j.ebiom.2018.01.043