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Activation of Neuregulin 1/ErbB Signaling Is Involved in the Development of TOCP-Induced Delayed Neuropathy

Organophosphate-induced delayed neuropathy (OPIDN) is characterized by progressive axonal degeneration and demyelination of the spinal cord and sciatic nerves. The neuregulin 1/epidermal growth factor receptor (ErbB) signaling pathway is crucial for axonal myelination. In this study, we investigated...

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Detalles Bibliográficos
Autores principales: Xu, Hai-Yang, Wang, Pan, Sun, Ying-Jian, Xu, Ming-Yuan, Zhu, Li, Wu, Yi-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925568/
https://www.ncbi.nlm.nih.gov/pubmed/29740279
http://dx.doi.org/10.3389/fnmol.2018.00129