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Single-Molecule Imaging of Wnt3A Protein Diffusion on Living Cell Membranes

Wnt proteins are secreted, hydrophobic, lipidated proteins found in all animals that play essential roles in development and disease. Lipid modification is thought to facilitate the interaction of the protein with its receptor, Frizzled, but may also regulate the transport of Wnt protein and its loc...

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Detalles Bibliográficos
Autores principales: Lippert, Anna, Janeczek, Agnieszka A., Fürstenberg, Alexandre, Ponjavic, Aleks, Moerner, W.E., Nusse, Roel, Helms, Jill A., Evans, Nicholas D., Lee, Steven F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925569/
https://www.ncbi.nlm.nih.gov/pubmed/29262368
http://dx.doi.org/10.1016/j.bpj.2017.08.060