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Single-Molecule Imaging of Wnt3A Protein Diffusion on Living Cell Membranes
Wnt proteins are secreted, hydrophobic, lipidated proteins found in all animals that play essential roles in development and disease. Lipid modification is thought to facilitate the interaction of the protein with its receptor, Frizzled, but may also regulate the transport of Wnt protein and its loc...
Autores principales: | Lippert, Anna, Janeczek, Agnieszka A., Fürstenberg, Alexandre, Ponjavic, Aleks, Moerner, W.E., Nusse, Roel, Helms, Jill A., Evans, Nicholas D., Lee, Steven F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925569/ https://www.ncbi.nlm.nih.gov/pubmed/29262368 http://dx.doi.org/10.1016/j.bpj.2017.08.060 |
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