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Neutrophil Microvesicles from Healthy Control and Rheumatoid Arthritis Patients Prevent the Inflammatory Activation of Macrophages

Microvesicles (MVs) are emerging as a novel means to enact cell-to-cell communication in inflammation. Here, we aimed to ascertain the ability of neutrophil-derived MVs to modulate target cell behaviour, the focus being the macrophage. MVs were generated in response to tumour necrosis factor-α, from...

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Detalles Bibliográficos
Autores principales: Rhys, Hefin I., Dell'Accio, Francesco, Pitzalis, Costantino, Moore, Adrian, Norling, Lucy V., Perretti, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925578/
https://www.ncbi.nlm.nih.gov/pubmed/29449195
http://dx.doi.org/10.1016/j.ebiom.2018.02.003