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DeepSynergy: predicting anti-cancer drug synergy with Deep Learning

MOTIVATION: While drug combination therapies are a well-established concept in cancer treatment, identifying novel synergistic combinations is challenging due to the size of combinatorial space. However, computational approaches have emerged as a time- and cost-efficient way to prioritize combinatio...

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Detalles Bibliográficos
Autores principales: Preuer, Kristina, Lewis, Richard P I, Hochreiter, Sepp, Bender, Andreas, Bulusu, Krishna C, Klambauer, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925774/
https://www.ncbi.nlm.nih.gov/pubmed/29253077
http://dx.doi.org/10.1093/bioinformatics/btx806