IL-1β suppresses cLTP-induced surface expression of GluA1 and actin polymerization via ceramide-mediated Src activation

BACKGROUND: Brain inflammation including increases in inflammatory cytokines such as IL-1β is widely believed to contribute to the pathophysiology of Alzheimer’s disease. Although IL-1β-induced impairments in long-term potentiation (LTP) in acute hippocampal slices and memory functions in vivo have...

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Detalles Bibliográficos
Autores principales: Tong, Liqi, Prieto, G. Aleph, Cotman, Carl W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925843/
https://www.ncbi.nlm.nih.gov/pubmed/29712570
http://dx.doi.org/10.1186/s12974-018-1158-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925843/
https://www.ncbi.nlm.nih.gov/pubmed/29712570
http://dx.doi.org/10.1186/s12974-018-1158-9

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