Loss of Perp in T Cells Promotes Resistance to Apoptosis of T Helper 17 Cells and Exacerbates the Development of Experimental Autoimmune Encephalomyelitis in Mice

T helper 17 (Th17) cells are crucial for the pathogenesis of multiple sclerosis (MS) in humans and experimental autoimmune encephalomyelitis (EAE) in animals. High frequency of Th17 cells and low sensitivity to activation-induced cell death (AICD) are detected in MS patients. However, the mechanisms...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Yan, Leng, Xiao, He, Yan, Li, Yan, Liu, Yuan, Liu, Yang, Zou, Qiang, Shi, Guixiu, Wang, Yantang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925960/
https://www.ncbi.nlm.nih.gov/pubmed/29740445
http://dx.doi.org/10.3389/fimmu.2018.00842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925960/
https://www.ncbi.nlm.nih.gov/pubmed/29740445
http://dx.doi.org/10.3389/fimmu.2018.00842

Ejemplares similares