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Growth Inhibition of A549 Human Lung Adenocarcinoma Cells by L‐Canavanine Is Associated with p21/WAF1 Induction

L‐Canavanine (CAV) is a higher plant nonprotein amino acid and a potent L‐arginine antimetabolite. CAV can inhibit the proliferation of tumor cells in vitro and in vivo, but little is known regarding the molecular mechanisms mediating these effects. We demonstrated that the treatment of human lung a...

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Detalles Bibliográficos
Autores principales: Ding, Yi, Matsukawa, Yoshizumi, Ohtani‐Fujita, Naoko, Kato, Daishiro, Dao, Su, Fujii, Takaaki, Naito, Yuji, Yoshikawa, Toshikazu, Sakai, Toshiyuki, Rosenthal, Gerald A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925972/
https://www.ncbi.nlm.nih.gov/pubmed/10076567
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00667.x