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Promotion by Sodium L‐Ascorbate in Rat Two‐stage Urinary Bladder Carcinogenesis is Dependent on the Interval of Administration

In our two‐stage model of rat urinary bladder carcinogenesis employing N‐butyl‐N‐(4‐hydroxybutyl)nitrosamine (BBN) as the initiator, sodium L‐ascorbate (Na‐AsA) exhibits dose‐dependent promotion. In the present study, in order to assess the possible reversibility of the promoting effects, we investi...

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Detalles Bibliográficos
Autores principales: Chen, Tian‐Xin, Wanibuchi, Hideki, Murai, Takashi, Kitano, Mitsuaki, Yamamoto, Shinji, Fukushima, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925984/
https://www.ncbi.nlm.nih.gov/pubmed/10076560
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00660.x