Reduction of the Side Effects of an Antitumor Agent, KRN5500, by Incorporation of the Drug into Polymeric Micelles

For intravenous (i.v.) injection of a water‐insoluble antitumor drug, KRN5500, we have successfully incorporated KRN5500 into polymeric micelles. In the present study, in vitro and in vivo antitumor activity against several human tumor cell lines and toxicity in mice of polymeric micelles incorporat...

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Detalles Bibliográficos
Autores principales: Matsumura, Yasuhiro, Yokoyama, Masayuki, Kataoka, Kazunori, Okano, Teruo, Sakurai, Yasuhisa, Kawaguchi, Takanori, Kakizoe, Tadao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925985/
https://www.ncbi.nlm.nih.gov/pubmed/10076575
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00675.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925985/
https://www.ncbi.nlm.nih.gov/pubmed/10076575
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00675.x

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