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Analysis of the c‐myc, K‐ras and p53 Genes in Methylcholanthrene induced Mouse Sarcomas

We have examined 63 methylcholanthrene (MCA)‐induced mouse sarcomas for possible correlations of mutations involving the c‐myc, ras and p53 genes. The c‐myc gene was found to be amplified in 18 of these sarcomas (29%). Polymerase chain reaction‐single strand conformation polymorphism (PCR‐SSCP) anal...

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Detalles Bibliográficos
Autores principales: Watanabe, Hiroshi, Shimokado, Kiyoshi, Asahara, Toshimasa, Dohi, Kiyohiko, Niwa, Ohtsura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925987/
https://www.ncbi.nlm.nih.gov/pubmed/10076563
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00663.x