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Differential Regulation of MMP‐9 and TIMP‐2 Expression in Malignant Melanoma Developed in Metallothionein/RET Transgenic Mice

We recently established a metallothionein‐I(MT)/RET transgenic mouse line in which skin melanosis, benign melanocytic tumor and malignant melanoma develop stepwise. Malignant melanoma cells but not benign melanocytic tumor cells had metastatic ability in transgenic mice. In the present study, we inv...

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Detalles Bibliográficos
Autores principales: Asai, Masami, Kato, Masashi, Asai, Naoya, Iwashita, Toshihide, Murakami, Hideki, Kawai, Kumi, Nakashima, Izumi, Takahashi1, Masahide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925989/
https://www.ncbi.nlm.nih.gov/pubmed/10076570
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00670.x