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In vivo Anti‐tumor Activity of a Novel Indolocarbazole Compound, J‐107088, on Murine and Human Tumors Transplanted into Mice

J‐107088 (6‐N‐(1‐hydroxymethyl‐2‐hydroxy)ethylamino‐12,13‐dihydro‐2,10‐dihydroxy‐13‐(β‐D‐glu‐copyranosyl)‐5H‐indolo[2,3‐a]‐pyrrolo [3,4‐c]carbazole‐5,7(6H)‐dione) is a derivative of NB‐506, an indolocarbazole compound previously reported as an anti‐tumor agent targeting topoisomerase L The optimal a...

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Detalles Bibliográficos
Autores principales: Arakawa, Hiroharu, Morita, Masashi, Kodera, Tsutomu, Okura, Akira, Ohkubo, Mitsuru, Morishima, Hajime, Nishimura, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925996/
https://www.ncbi.nlm.nih.gov/pubmed/10595746
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00691.x