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A Selective Cyclooxygenase‐2 Inhibitor Suppresses Tumor Growth in Nude Mouse Xenografted with Human Head and Neck Squamous Carcinoma Cells

The anti‐tumor effect of a selective cyclooxygenase (COX)‐2 inhibitor, JTE‐522, was examined with the human head and neck squamous cell carcinoma cell line KB. KB cells do not produce prostaglandin (PG)‐E2. In vitro, JTE‐522 induced an increase of G1 phase‐arrested cells, suppression of platelet‐der...

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Detalles Bibliográficos
Autores principales: Nishimura, Goshi, Yanoma, Syunsuke, Mizuno, Hiromi, Kawakami, Koji, Tsukuda, Mamoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925997/
https://www.ncbi.nlm.nih.gov/pubmed/10595745
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00690.x