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Interaction of Docetaxel (“Taxotere”) with Human P‐Glycoprotein

The interaction of docetaxel (“Taxotere”) with P‐glycoprotein (P‐gp) was examined using porcine kidney epithelial LLC‐PK(1) and LLC‐GA5‐COL150 cells, overexpressing human P‐gp selectively on the apical plasma membrane by transfection of human MDR1cDNA into the LLC‐PK(1) cells. The basal‐to‐apical tr...

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Detalles Bibliográficos
Autores principales: Shirakawa, Katsuro, Takara, Kohji, Tanigawara, Yusuke, Aoyama, Nobuo, Kasuga, Masato, Komada, Fusao, Sakaeda, Toshiyuki, Okumura, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926029/
https://www.ncbi.nlm.nih.gov/pubmed/10665657
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00723.x