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Frameshift Mutations and a Length Polymorphism in the hMSH3 Gene and the Spectrum of Microsatellite Instability in Sporadic Colon Cancer

Mutations in the hMSH3 gene in sporadic colon cancer with microsatellite instability (MSI) were investigated, since several mismatch repair genes were known to be mutated in cancers with MSI, but only deletions in the (A)(8) region in the hMSH3 gene have been reported. We also analyzed the relations...

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Detalles Bibliográficos
Autores principales: Orimo, Hideo, Nakajima, Eiitsu, Ikejima, Miyoko, Emi, Mitsuru, Shimada, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926037/
https://www.ncbi.nlm.nih.gov/pubmed/10665647
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00713.x