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Evaluation of Antivascular and Antimitotic Effects of Tubulin Binding Agents in Solid Tumor Therapy

Tubulin binding agents (TBAs) reduce tumor perfusion and inhibit mitosis of tumor cells in solid tumors, but it is not clear which effects contribute to the suppression of solid tumor growth. We evaluated the antivascular and antimitotic effects of several TBAs, combretastatin A‐4 (CS A‐4) phosphate...

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Detalles Bibliográficos
Autores principales: Nihei, Yukio, Suzuki, Manabu, Okano, Akira, Tsuji, Takashi, Akiyama, Yukio, Tsuruo, Takashi, Saito, Sachiko, Hori, Katsuyoshi, Sato, Yasufumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926039/
https://www.ncbi.nlm.nih.gov/pubmed/10665658
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00724.x