Overexpression of MDM2 in MCF‐7 Promotes Both Growth Advantage and p53 Accumulation in Response to Estradiol

The overexpression of the oncogene product MDM2 is often observed in human breast cancer cells, especially in estrogen receptor (ER)‐positive ones. To study the role of MDM2 protein in ER‐positive breast cancer, we have established cell lines derived from MCF‐7 which stably express increased and dec...

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Detalles Bibliográficos
Autores principales: Saji, Shigehira, Nakashima, Shigeru, Hayashi, Shin‐ichi, Toi, Masakazu, Saji, Shigetoyo, Nozawa, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926053/
https://www.ncbi.nlm.nih.gov/pubmed/10189892
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00735.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926053/
https://www.ncbi.nlm.nih.gov/pubmed/10189892
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00735.x

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