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Overexpression of MDM2 in MCF‐7 Promotes Both Growth Advantage and p53 Accumulation in Response to Estradiol
The overexpression of the oncogene product MDM2 is often observed in human breast cancer cells, especially in estrogen receptor (ER)‐positive ones. To study the role of MDM2 protein in ER‐positive breast cancer, we have established cell lines derived from MCF‐7 which stably express increased and dec...
Autores principales: | Saji, Shigehira, Nakashima, Shigeru, Hayashi, Shin‐ichi, Toi, Masakazu, Saji, Shigetoyo, Nozawa, Yoshinori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926053/ https://www.ncbi.nlm.nih.gov/pubmed/10189892 http://dx.doi.org/10.1111/j.1349-7006.1999.tb00735.x |
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