Circumvention of 5‐Fluorouracil Resistance in Human Stomach Cancer Cells by Uracil Phosphoribosyltransferase Gene Transduction

A human stomach cancer cell line with acquired resistance to 5‐fluorouracil (5‐FU), NUGC‐3/5FU/L, has been found to possess reduced ability to convert 5‐FU into active metabolites. We attempted in vitro gene therapy for this 5‐FU‐resistant cell line. NUGC‐3 and NUGC‐3/5FU/L cells were infected with...

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Detalles Bibliográficos
Autores principales: Inaba, Makoto, Sawada, Hiroko, Sadata, Akiko, Hamada, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926061/
https://www.ncbi.nlm.nih.gov/pubmed/10359051
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00754.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926061/
https://www.ncbi.nlm.nih.gov/pubmed/10359051
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00754.x

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