Mechanism of Oxidative DNA Damage Induced by a Heterocyclic Amine, 2‐Amino‐3,8‐dimethylimidazo[4,5‐f]quinoxaline

Adduct formation has been considered to be a major causal factor of DNA damage by carcinogenic heterocyclic amines. By means of experiments with (32)P‐labeled DNA fragments and an electrochemical detector coupled to a high‐pressure liquid chromatograph, we investigated whether the N‐hydroxy metaboli...

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Detalles Bibliográficos
Autores principales: Murata, Mariko, Kobayashi, Mikiko, Kawanishi, Shosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926070/
https://www.ncbi.nlm.nih.gov/pubmed/10359040
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00743.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926070/
https://www.ncbi.nlm.nih.gov/pubmed/10359040
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00743.x

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