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Mechanism of Oxidative DNA Damage Induced by a Heterocyclic Amine, 2‐Amino‐3,8‐dimethylimidazo[4,5‐f]quinoxaline
Adduct formation has been considered to be a major causal factor of DNA damage by carcinogenic heterocyclic amines. By means of experiments with (32)P‐labeled DNA fragments and an electrochemical detector coupled to a high‐pressure liquid chromatograph, we investigated whether the N‐hydroxy metaboli...
Autores principales: | Murata, Mariko, Kobayashi, Mikiko, Kawanishi, Shosuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926070/ https://www.ncbi.nlm.nih.gov/pubmed/10359040 http://dx.doi.org/10.1111/j.1349-7006.1999.tb00743.x |
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