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Somatic Mutation of the APC Gene in Thyroid Carcinoma Associated with Familial Adenomatous Polyposis

We report the existence of both germline and somatic mutations of the APC gene in thyroid carcinomas from familial adenomatous polyposis (FAP) patients. One papillary thyroid carcinoma from a 20‐year‐old woman, with germline mutation of the APC gene (TCA to TGA at codon 1110), showed a somatic mutat...

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Detalles Bibliográficos
Autores principales: Iwama, Takeo, Konishi, Motoko, Iijima, Takeru, Yoshinaga, Keigo, Tominaga, Takeshi, Koike, Morio, Miyaki, Michiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926080/
https://www.ncbi.nlm.nih.gov/pubmed/10363573
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00757.x