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Differences in Substrate Specificity among Glutathione Conjugates (GS‐X) Pump Family Members: Comparison between Multidrug Resistance‐associated Protein and a Novel Transporter Expressed on a Cisplatin‐resistant Cell Line (KCP‐4)

The substrate specificity of primary active transporters expressed on two kinds of human epidermoid KB‐3‐1 derived cell lines, C‐A500 and KCP‐4, was examined; the former expresses multi‐drug resistance‐associated protein (MRP1), whereas the latter is resistant to cis‐diammine‐dichloroplatinum (II) (...

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Detalles Bibliográficos
Autores principales: Ueda, Kaoru, Suzuki, Hiroshi, Akiyama, Shin‐ichi, Sugiyama, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926082/
https://www.ncbi.nlm.nih.gov/pubmed/10363583
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00767.x