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Differences in Substrate Specificity among Glutathione Conjugates (GS‐X) Pump Family Members: Comparison between Multidrug Resistance‐associated Protein and a Novel Transporter Expressed on a Cisplatin‐resistant Cell Line (KCP‐4)
The substrate specificity of primary active transporters expressed on two kinds of human epidermoid KB‐3‐1 derived cell lines, C‐A500 and KCP‐4, was examined; the former expresses multi‐drug resistance‐associated protein (MRP1), whereas the latter is resistant to cis‐diammine‐dichloroplatinum (II) (...
Autores principales: | Ueda, Kaoru, Suzuki, Hiroshi, Akiyama, Shin‐ichi, Sugiyama, Yuichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926082/ https://www.ncbi.nlm.nih.gov/pubmed/10363583 http://dx.doi.org/10.1111/j.1349-7006.1999.tb00767.x |
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