Enhancement of the Anti‐tumor Effect of 5′‐Deoxy‐5‐fluorouridine by Transfection of Thymidine Phosphorylase Gene into Human Colon Cancer Cells

Thymidine phosphorylase (dThdPase) is an enzyme that converts 5′‐deoxy‐5‐fluorouridine (5′DFUR) to the toxic substance 5‐fluorouracil (5‐FU); it is also known to be a platelet‐derived endothelial cell growth factor. In order to investigate the feasibility of suicide gene therapy against colorectal c...

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Detalles Bibliográficos
Autores principales: Kanyama, Hiroki, Tomita, Naohiro, Yamano, Tomoki, Miyoshi, Yasuo, Ohue, Masayuki, Fujiwara, Yoshiyuki, Sekimoto, Mitsugu, Sakita, Isao, Tamaki, Yasuhiro, Monden, Morito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926090/
https://www.ncbi.nlm.nih.gov/pubmed/10363585
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00769.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926090/
https://www.ncbi.nlm.nih.gov/pubmed/10363585
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00769.x

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