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Effects of d‐Galactosamine Hydrochloride and Partial Hepatectomy on Spontaneous Hepatic Injury and Hepatocarcinogenesis in Long‐Evans Cinnamon Rats

To examine the effect of nongenotoxic chemicals on hepatocarcinogenesis in Long‐Evans Cinnamon (LEC) rats, we gave 6‐week‐old male and female LEC rats (n=18) weekly subcutaneous injections of d‐galactosamine hydrochloride (GalN, 300 mg/kg) in 0.9% NaCl or only 0.9% NaCl for 50 weeks, and killed them...

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Detalles Bibliográficos
Autores principales: Jiao, Zhongxian, Ohnishi, Takamasa, Bando, Yoshimi, Chone, Yoshifumi, Kitaura, Keisuke, Uehara, Hisanori, Suzuki, Yasuo, Nakamura, Toshikazu, Izumi, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926103/
https://www.ncbi.nlm.nih.gov/pubmed/10391088
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00775.x