Membrane Transport and Antitumor Activity of Pirarubicin, and Comparison with Those of Doxorubicin

We have compared the membrane transport and antitumor activity of pirarubicin with those of doxorubicin in M5076 ovarian sarcoma, which exhibits low sensitivity to doxorubicin. Pirarubicin was rapidly taken up by M5076 cells and the intracellular concentration of pirarubicin reached more than 2.5‐fo...

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Detalles Bibliográficos
Autores principales: Sugiyama, Tomomi, Sadzuka, Yasuyuki, Nagasawa, Kazuki, Ohnishi, Noriaki, Yokoyama, Teruyoshi, Sonobe, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926135/
https://www.ncbi.nlm.nih.gov/pubmed/10470291
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00814.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926135/
https://www.ncbi.nlm.nih.gov/pubmed/10470291
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00814.x

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